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In this chapter, we briefly review some aspects of the biology and physiology of oral melanocytes, the function of melanin in the oral epithelium, and the features of several different oral mucosal melanin hyperpigmentations, including physiological hyperpigmentation, tobacco-related melanosis, human immunodeficiency virus (HIV)-associated melanosis, melanotic maculae, naevomelanocytic naevus, and oral mucosal melanoma

For qualified laboratory research only

The melanocortin 3 receptor (MC3R) might be found in a range of tissues, potentially including the brain and the placenta

By encouraging melanin production and helping restore a more uniform skin tone