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This severe metabolic blockade reduces the transmitter content of individual vesicles by more than 50%, resulting in a dramatic decrease in quantal size and a rapid, dose-independent decay of the sympathomimetic response (Sulzer et al, 1995

Activation of STING via cGAS-mediated recognition of double-stranded DNA results in phosphorylation and nuclear localization of IRF3, culminating in the production of type I interferons (IFN) and induction of local immune responses 17

They are not for human or animal use, consumption, or application, and are not approved by the FDA for any therapeutic, diagnostic, or medical purposes