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Also, recent evidence suggests that GSH plays a crucial role in the control of epigenetic mechanisms 3,4,28,29,30,31 either independently or by redox phenomenon

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Other studies are focusing on reinforcing the safety and efficacy of drugs already available Fabagal and comparing to its active comparator (NCT06081062), or combined enzyme replacement therapies with Fabryzyme and agalsidase beta (NCT05843916), and pegunigalsidase alfa to assess safety, pharmacodynamics and efficacy (NCT06328608), as well as gene editing studies involving AAV vectors to try more permanent approaches of treatment (ChiCTR2300073886, NCT05629559, NCT04040049)

Unless and until large, well-designed human trials clarify safety and efficacy, BPC-157 remains an unapproved peptide, subject to regulatory controls and compliance requirements in drug-tested populations