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Redox Biology;2015 Jul Guoyao Wu, Yun-Zhong Fang, Sheng Yang, Joanne R Lupton, Nancy D Turner

6 As highly dynamic organelles, mitochondria undergo rapid and continuous fusion and fission cycles, termed mitochondrial dynamics

While it is well known that enhanced insulin sensitivity and low insulin levels are associated with an improved survival, there is evidence showing that attenuation of growth hormone/IGF-1 axis may have beneficial effects in extending lifespan in humans