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Firstly, most of commercially available plant-based proteins are known for having a deficiency in essential amino acids, such as leucine, lysine, or methionine [i.e., although they may have all the essential amino acids, their amounts are not enough to meet the parameters set by the World Health Organization (WHO)]

With few exceptions, such as ruminants which depend on the biosynthesis of cobalamin by resident microbes, most animals rely on its bioaccumulation in the food chain [2]

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