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While NNMT influences energy metabolism in both adipose tissue and liver, its expression suppresses NAD + levels specifically in adipose tissue

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However, when the assay was repeated with 5-amino-6-fluoro-1MQ, an analogue of 5-amino-1MQ that did not interfere with the NAMPT assay, no inhibition of NAMPT was observed with analogue concentrations between 30 and 600 M (data not shown)