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Furthermore, the complex interplay of immune cells, endothelial responses, and microbial metabolites in vivo is difficult to fully capture in experimental models (Limbad et al., 2024)

This targeted action prompts the pituitary gland to increase GH secretion, potentially leading to benefits such as enhanced muscle growth and fat loss

Available online: 89.Fintini D., Brufani C., Cappa M

Finally, the process demands careful balancing between maximizing extraction efficiency and preventing compound degradation, which remains a key limitation in fully harnessing pressurized liquid extraction for polyphenol extraction (77)