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In conclusion, although many reports previously evidenced the regulation of signaling pathways by GSTs in various in vitro cell systems, we demonstrate for the first time that the invalidation of Gstp1/p2 affects multiple key events of the hepatocyte cell cycle in vivo after PH

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Consequently, focusing on these molecular regulators presents a great opportunity for innovative therapeutic techniques designed to maintain RBC deformability, reduce hemolysis, and enhance transfusion results (23, 45)

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