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Superoxide dismutase is an enzyme that decreases tissue destruction by eliminating the superoxide radical in most cells when subjected to oxygen (Pinmanee et al., 2023)

XS: Conceptualization, Writingoriginal draft, Validation

Although preclinical studies suggest antitumor activity via modulation of the cell cycle, apoptosis, and angiogenesis, large-scale randomized controlled trials have not demonstrated a clear benefit in terms of cancer incidence or mortality (11)

TNF-alpha, interleukin-6 (IL-6), interleukin-1-beta (IL-1B), and interferon-gamma (IFN-gamma) drive persistent inflammation that damages tissue over time