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Description

Dosage should begin conservatively and adjust based on tolerance and clinical markers

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The mutation frequency of TSC2 was significantly higher in the MVI-positive group (40%) than the MVI-negative group (16.3%) (p=0.016)

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Moreover, PI3K/AKT/mTOR oncogenic cascade pathways are frequently dysregulated in several types of cancer, further enhancing lipogenic activities

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Since brain function is an immediate requirement in most cases, acetylation is often the dominant pathway (Iulia et al., 2017)

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