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NRH:quinone oxidoreductase2 (NQO2)

[DOI] [PMC free article] [PubMed] [Google Scholar] 227.Sundaran I.K., Sarangi D.D., Sundararajan V., George S., Mohideen S.S

Structureactivity relationship of ENL-driven CRBN binding To evaluate the mechanism of CRBN engagement further, we assessed the dHTC1 structureactivity relationship (SAR) by replacing the sulfamide connection with an amide, yielding rac -dHTC1-amide ( 5 ), or with a urea, yielding rac -dHTC1-urea ( 6 )