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doi: 10.3390/ijms23116086, 22

The synergistic interplay among withanolides, sitoindosides, and saponins seemingly propels the adaptogenic attributes of Ashwagandha by modulating the responses of stress hormones, regulating neurotransmitter systems, and augmenting the expression of neurotrophic factors

Stressful states like starvation cause inhibition on mTORC pathway thereby causing increased autophagy and release of nutrients as compensatory mechanism for starvation