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Discovery of a dual inhibitor of nqo1 and gstp1 for treating glioblastoma

Arginine depletion inhibits the dephosphorylation of the actin-binding protein cofilin, thereby impairing immunological synapse formation and T cell activation [240,241,242]

Haoran Chen, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

BALB/c mice were intranasally administered 0.5 g recombinant murine IL-33 while concurrently receiving intraperitoneal injections of melatonin (10 mg/kg) and Luzindole (30 mg/kg) ( Figure 2A )