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10.1016/s0022-3956(03)00022-0 J

For instance, a size-dependent study of surface-modified poly(lactic-co-glycolic acid) (PLGA) nanoparticles demonstrated that particles with the smallest size (60 nm) exhibited the highest brain accumulation compared with larger particles, suggesting that smaller nanoparticles traverse the BBB more efficiently than larger particles (Meng et al., 2022)

Pharmacokinetic Profile Route of Administration Subcutaneous Route of Administration : Subcutaneous Injection Formulation & Handling Supplied as a lyophilized powder or aqueous solution

Organic nanoparticles, mainly polymer and lipid nanoparticles, hold great promise for delivering drugs into the brain