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L.GoncalvesR

1) and suggest robust and active maintenance of the cytosolic NADP redox state even under severe oxidative challenge, which is in stark contrast to previous observations of a highly volatile cytosolic NAD redox state as monitored by Peredox 13,23

doi: 10.1515/znc-2024-0116 3 ShangSYangHQuLFanDDengJ

Ferroptosiss involvement is reinforced by the recent finding of lipid hydroperoxides in the pulmonary drainage fluid of ARDS patients ( Lipid peroxidation, the glutathione (GSH)/GPX4 axis, and iron metabolism comprise the central signaling mechanism of ferroptosis