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In addition, the quality of the extraction and the rate of protein extraction may be significantly reduced by conventional methods

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas

Beyond primary tumor associated mtDNA mutations, mitochondrial DNA damage induced by chemotherapy or radiotherapy may further exacerbate this process [385,386,387]

To determine if they could be fully restored after preheated APR-246 inhibition, preheated APR-246-treated Trx1 was incubated with either 50 nM TrxR and 0.25 mM NADPH (Fig