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For example, HIV-1 Tat acts as a growth factor for KS-derived endothelial cells (Guo et al., 2004

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Studies have revealed that lactylation integrates microenvironmental cues through a metabolismepigeneticsimmunity axis, serving as a pivotal regulator of inflammatory polarization, immune-cell control such as macrophage phenotype switching) and the dynamic progression of disease (44)