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Thomas et al., 2012), and SCFAs could regulate gut immunity and genes expression of the host (Chang et al., 2014)

Heightened oxidative stress resulting from an excess of iron is a significant contributor to cellular damage

Genes involved in signal transduction and immunological response, as well as the expression of certain miRNAs (miR-145, miR-148-5p, and miR-592), were shown to be altered in tandem with GPER activation, as was the extracellular-signal-regulated kinase (ERK) signaling pathway (251)