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Several animal studies, including the following have supported the benefit of CoQ10 treatment in ALS: In an animal model of familial ALS, administration of coenzyme Q10 significantly extended life span and oral administration significantly increased CoQ10 concentrations in the brains and mitochondria of the test animals (Matthews 1998)

"Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion"

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The penalty for 1 ppm m / z difference between annotated formula and measured m / z was set at 0.5