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Neil K Gibbs, L-Histidine Supplementation in Adults and Young Children with Atopic Dermatitis (Eczema), The Journal of Nutrition , Volume 150, Issue Supplement_1, October 2020, Pages 2576S2579S, Song X, Qu H, Yang Z, Rong J, Cai W, Zhou H

These regions supported the physiological functions of AR as a ligand-dependent transcription factor, allowing testosterone or 5-dihydrotestosterone (DHT) to bind to AR, stabilize the receptor-DNA complex when dimerized AR binds to DNA at specific androgen-response elements (ARE) [20], and modulate transcriptional activation of androgen-dependent genes [21]

Large-scale, controlled studies are needed before any conclusions can be drawn

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