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The assessment of both NR and AGD in guideline studies is therefore still recommended - We recommend an international standardization to reduce the lab-to-lab variability in the outcome of NR assessments - NR may be more specific than AGD with regard to anti-androgenic mode of action (specific to the DHT-AR signaling axis), with AGD seemingly also more vulnerable to perturbations outside the canonical DHT-AR signaling axis

Secreted protein was purified from supernatant using CaptureSelect Human albumin affinity matrix (ThermoFisher, #191297005) by elution with 2 M MgCl 2 , pH 7.4

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How to Lower Hematocrit While on TRT You can safely reduce hematocrit on TRT through therapeutic phlebotomy, blood donation, asking your doctor to change your TRT dose or delivery system, and making lifestyle changes