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Most purification schemes require the use of more than one of these types of chromatographic procedures to yield the necessary purity for downstream applications

The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)

Similarly, the Zhigancao Decoction has been shown to alleviate arrhythmias and improve autonomic nervous system stability, while concurrently reducing systemic inflammation (34)

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