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Screening of 289 patients with coronary artery disease and 255 control subjects revealed 77 individuals with the G-50T SNP (17.3% of CAD patients, 10.6% of control subjects

3 shows the activity of the enzymes GPx (A) and GRd (B), as well as the GSSG/GSH ratio (C) in the three study groups

The observed protective effect coincided with alterations in the expression of genes associated with oxidative balance (Noxa1, Gpx1, Ccs, and Sod1) and inflammation (Mpo, Ncf, Il1b, and Il4)