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Ascorbate acid (AscH 2 ) can be readily converted at physiological pH to the ascorbate anion (AscH )

Studies from multiple independent groups across musculoskeletal injury, gastrointestinal disease, vascular injury, and neurological insult have reported positive outcomes

In vitro studies have shown that certain flavonoids, at high concentrations, can inhibit the growth of probiotic bacteria such as Lactobacillus app., while promoting the proliferation of opportunistic pathogens and inducing the accumulation of harmful metabolites, including H 2 S and NH 3 (Pan et al., 2023), which may adversely affect gut microbial homeostasis under specific conditions

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