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Sustained lipid peroxidation leads to the accumulation of harmful molecules such as lipid peroxides, aldehydes, and their conjugates, ultimately resulting in rupture of the plasma membrane [105,106]

As crucial regulators of local immune responses and tissue repair, macrophages in diabetic wounds show dysregulated switching from M1 to M2, resulting in a poor regenerative environment, exacerbated tissue damage, and delayed wound healing 63

(Of course, my mama heart doesnt ever want any twins to be separated at birth, but twin and separated twin studies are always so interesting