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AD is the most common cause of dementia and is a degenerative disorder of the characterized by memory loss, and neuropathologically by accumulation of A in neurofibrillary tangles

The terminal half-life was 5.58 h after intravenous administration and 6.25 h after oral administration

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The phenotype-specific dosing recommendations could serve as a reference for developing personalized therapeutic guidelines to optimize clinical outcomes and minimize adverse effects in this vulnerable population