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They are widely used in research, therapeutics, and biotechnology

Nat Med 2019, 25: 554560

REDEFINE 1 adults with overweight/obesity, no diabetes GI adverse events were reported in 79.6% of CagriSema participants vs 39.9% on placebo

Weight Loss Efficacy: Head-to-Head Comparison Primary Phase 3 Results Key Finding: Retatrutide produces 8.3 percentage points more weight loss than CagriSema at 68 weeks