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doi: 10.1038/s41598-018-32356-8 92 DornanDWertzIShimizuHArnottDFrantzGDDowdPet al

In contrast, induction of c-Myc mRNAs occurred earlier, and their levels remained higher at several time points in the Gstp1/2 / regenerating livers compared with the WT control livers (Figure 5a)

Liquid chromatography-tandem mass spectrometry was employed to quantify plasma TMAO, choline and their related metabolites, encompassing TMA, l-carnitine, betaine and dimethylglycine (DMG), which are betaine-related metabolites (Reference Wiedeman, Barr and Green14)