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It has been found that hypoxia causes -catenin to be expressed and accumulate in HCC cell lines, which facilitates invasion and metastasis (159)

Dalle F, Wchtler B, LOllivier C, Holland G, Bannert N, Wilson D, Hube B

( Epub 2020 Mar 9 )

For example, S100A8 deficiency induces a severe phenotype of psoriasis-like cutaneous inflammation, and rapid synchronous early resorption of the mouse embryo (119)