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By contrast, GRK2 also negatively regulates 2 -adrenergic receptor [40] and dopamine D 1 receptor (D 1 R)/adenylyl cyclase signaling [41], which should result in vasoconstriction

On the other hand, ferroptosis inhibitors, including ferrostatin-1, iron chelators, and antioxidants, have shown potential in protecting granulosa cells from ferroptosis and oxidative damage, though clinical evidence supporting these strategies is currently lacking

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