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doi: 10.1016/j.tox.2021.153048 78 Grau-PerezMKuoCCSpratlenMThayerKAMendezMAHammanRFet al

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9 Nrf2 is usually locked in the cytoplasm, but activation by DMF/MMF allows it to translocate to the nucleus where it activates a pathway of genes involved in antioxidant responses, detoxification, and the activity of cytoprotective anti-inflammatory factors

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