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For instance in the SCALE trials, non-completing patients typically discontinued liraglutide 3.0 mg due to tolerability issues, whereas non-completing patients typically discontinued placebo due to lack of effect, and there are no strong arguments to suggest that the patients who discontinued placebo would also have been the patients who would experience tolerability issues had they been randomized to liraglutide 3.0 mg instead

Topical therapies

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Peptide inhibitors or antagonists of cell surface proteins Immune checkpoint inhibitors The advent of immune checkpoint inhibitors (ICIs) has revolutionized the field of tumor therapy and promoted the development of more immune checkpoint blockades 83