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While occasional constipation is usually not serious, chronic constipation can impact quality of life and may signal underlying health problems

No cell-related safety issues were encountered in this trial, although the patients receiving 18*10 6 MSCs showed a higher incidence of adverse effects ( Lastly, several human growth factor-based phase I/II clinical trials were started to evaluate the safety, tolerability, and preliminary effectiveness of intradiscal delivery of growth and differentiation factor-5 (GDF-5) as compared with placebo (sterile water/vehicle control) in human patients with early lumbar disc degeneration in the United States, Australia, and the Republic of Korea

Less constant fatigue

They are included solely for background reading and must not be interpreted as evidence of safety, efficacy, or suitability for human use