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Key areas requiring further investigation include cumulative effects of chronic exposure, drug interactions, and impact on various organ systems

Collectively, to systematically investigate tissue- and cell-type-specific expression profiles of E3 Ub ligases, under normal or diseased/stressed states, will be an attracting topic in the next decade either to comprehensively understand the biology of E3 ligases in different diseases/stresses or to extend PROTAC applications

Previous research has shown that granuloma formation occurs approximately seven days post-PBMC infection with M