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Endometriosis triggers excessive activation of primordial follicles via PI3K-PTEN-akt-foxo3 pathway

Bogan KL, Evans C, Belenky P, Song P, Burant CF, Kennedy R, Brenner C: Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside

EdwardsBJUsmaniSRaischDWMcKoyJMSamarasATBelknapSMet al

These studies provide the scientific basis for the development of new diabetes treatments, and cynaroside as a natural flavonoid holds promise as an effective drug for diabetes therapy, especially for diabetic patients with higher postprandial glucose