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Nature 480, 109112 (2011)

To facilitate further data processing and improve interpretability, we performed channel-wise normalization, scaling values between 0 and 1

elegans orthologue of human adh-5 gene (H24K24.3) was knocked out using the CRISPR/Cas9 system as previously reported: The preassembled CRISPR/Cas9 ribonucleoprotein complexes and linear single stranded DNAs as repair templates were directly injected into the gonad of young adult hermaphrodites 61