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Leucine supplementation attenuates macrophage foam-cell formation: studies in humans, mice, and cultured macrophages

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Arthritis Res Ther 15, 221 (2013)

3 Overview of autophagy and its biological significance Autophagy is a conserved, lysosome-dependent catabolic pathway, named from the Greek term for self-eating, that removes aberrant proteins, damaged organelles (e.g., mitochondria and ER), and invading pathogens