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The mechanism by which SIRT1 hinders the activity of several redox-sensitive pro-inflammatory mediators, such as NF-kB and NLRP3, can shed light on this phenomenon

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Rare familial cases describe frontotemporal dementia (FTD) emerging in individuals initially diagnosed with schizophrenia, often linked to GRN, MAPT, or valosin-containing protein (VCP) mutations (184)