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These bigwigs, along with the previously obtained induced and reduced peaks in bed format, were input into deeptools computeMatrix, and the output was plotted using deeptools plotHeatmap reference-point

Additionally, dietary potassium and sodium should be controlled according to the comorbidities, medicine use, blood pressure and test results

and 3) tetra-spanning proteins of the claudin and tight junction-associated MARVEL protein (TAMP) families, which include occludin, tricellulin, and MarvelD3 (Figure 1)