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One of the reasons glutathione is so popular in skin care is its ability to brighten and even out skin tone

doi: 10.1038/nature08938 38 EndemannG.StantonL.MaddenK

This results in closure of the ATP-sensitive K + channels, decreasing the hyperpolarising outward K + flux, depolarising the plasma membrane and opening voltage-gated Ca 2+ channels to increase the influx of extracellular Ca 2+ , which is a primary driver of the mechanism of glucose-stimulated insulin secretion (GSIS)