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The primary concern raised by the Norwegian IRB was that this RCT was violating the principle of clinical equipoise

Hydroxocobalamin is the form the NHS uses because it lingers in the body longer than cyanocobalamin, and its pharmacology supports dosing intervals of up to three months once levels are stable

What none of them has, alone or blended, is a completed human trial, so the blend belongs firmly in the research-and-hypothesis column rather than the proven-protocol one