oral melanotic macule vs nevus Macules, Naevi, and Melanoma Clinical features of acquired melanocytic

Metabolites altered in ME/CFS patients include a decrease of myo-inositol, a putative marker of glial dysfunction (Noda et al., 2018), in the anterior cingulate cortex (Godlewska et al., 2021), and an increase of choline mainly found in glial cells and thought to indicate an increased cell membrane turnover notably due to reparative gliosis in the left anterior cingulate (Mueller et al., 2020) and basal ganglia (Tanaka et al., 2006

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