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Paderno A, Mattavelli D, Rampinelli V, Grammatica A, Raffetti E, Tomasoni M, et al

MGF's E-domain is thought to act through a distinct receptor or membrane interaction to activate quiescent satellite cells before the Ec-domain is cleaved and the remaining IGF-1 sequence engages classical IGF-1R [12]

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In parallel to the development of DOS, DNA-encoded libraries (DELs) have emerged as an effective, efficient screening strategy to identify protein binders