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Yes, it can

While pyridoxine (vitamin B6) is typically considered helpful in reducing vomiting and nausea, the American Academy of Family Physicians (AAFP) mentions that cyanocobalamin (vitamin B12) also significantly reduced vomiting episodes in pregnant women compared with placebo, indicating its role in nausea and vomiting management

Left alone long enough, vitamin B12 deficiency leads to a host of conditions, many that Metformin was supposed to prevent, including: Increased rates peripheral neuropathy (nerve pain and numbness that leads to all sorts of problems for diabetics) Pernicious anemia (the body cant make enough red blood cells because of a B12 deficiency

Including ones that involve removing part of stomach and/or small intestine