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In addition to these findings, in vivo evidence of IgG1-3 pathogenicity is provided by a model in which a mouse knockout of murine IgG1-equivalent to human IgG4-developed myasthenic features when immunized against MuSK

10.1182/blood.v92.4.1191.416k15_1191_1198 31 LanganR

The medium coefficient of variation for each quantitative dataset is provided in each Supplementary Dataset legend

Novel defects in collagen XII and VI expand the mixed myopathy/EhlersDanlos syndrome spectrum and lead to variant-specific alterations in the extracellular matrix