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Helsley RN et al

However, progein was identified to be the critical target of farnesyltransferase inhibitors (FTIs) (Yang et al., 2010) and one FTI called lonafarnib have been tested in a cohort study which showed a significantly lower mortality rate (hazard ratio, 0.12) after a median of 2.2 years of follow-up ( The investigation of the GPX4 function was far ahead of the emergence of ferroptosis