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Oxidative metabolism signatures predict response to 5FU-based chemotherapy treatment Given this robust adaptation to facilitate cellular survival in cancer cells treated with 5FU, we next postulated that elevated mitochondrial metabolism may be a predictor of response to 5FU-based chemotherapy

As a result, reviewers generally describe these findings as suggestive rather than definitive

As part of this review, we report knowledge on regulatory factors, the link between the regulation of the mRNA and the expression of GPx activity, the relationship between abnormal expression of GPx1 and the ethology of diseases, and finally the roles of GPx in different diseases especially in chronic diseases

The following section explores recent progress in these nanoprobes for sensitive and selective GSH detection