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Conclusions PDAC remains a formidable clinical challenge, characterized by a highly aggressive phenotype, a profoundly immunosuppressive TME, and notorious resistance to conventional and emerging immunotherapies

Balancing benefits and interactions ensures safe outcomes

Below, the catalytic mechanism of E

We used neurons isolated from aged 3xTg-AD Alzheimers model mice and a novel genetically encoded fluorescent GTP sensor (GEVAL) to evaluate live GTP levels in situ