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IP3 may trigger the release of calcium ions (Ca2+) from intracellular stores, while DAG may activate protein kinase C (PKC)

wishing you pain free times M Thanks, I was back yesterday but as the bleeding is starting longer after each pack I've to try another three months and see if it settles (2nd pack had 9 period free days, 3rd pack 13- the doctor reckons in three months I should get my full 3 weeks free)