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Dox pretreatment alone delayed the onset of ferroptosis (i.e., increased D O ) in response to erastin2 in Control cells capable of expressing p21, albeit not to the same extent as nutlin-3 treatment (Fig 2B and C)

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Using genetic and pharmacological approaches in yeast, mammalian cells and Drosophila , we found that GPx activity robustly ameliorates Huntington's diseaserelevant metrics and is more protective than other antioxidant approaches tested here

Myasthenia gravis can manifest a variety of symptoms, varying from person to person